Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1754382Generated: November 3, 2026

HCID 86257708, compound → 1-(4-fluorophenyl)-1H-pyrazol-4-amine

https://huagongshe.com/reaction/1754382

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86257708HCID 86257708—
CatalystPalladiumHCID 23938—
SolventEthanolHCID 702—
Product1-(4-fluorophenyl)-1H-pyrazol-4-amineHCID 4353171596.2%

Reaction Steps

A mixture of 1-(4-fluorophenyl)-4-nitropyrazole (0.820 g, 3.96 mmol) and 10% Pd/C (0.133 g, 50% wet by wt) in EtOH (50 mL) was fitted onto a Parr apparatus and agitated under H2 at 40 psi for 40 min. The reaction mixture was then filtered through filter paper. The filtrate was collected and concentrated in vacuo to give 1-(4-fluorophenyl)pyrazol-4-amine as an oil (0.675 g, 96%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09169248B2
Source datasetuspto-grants-2015_10
ORD IDord-a18390c029154e59af9a3eb968c86735
Source noteuspto-grants-2015_10