HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86257708, compound → 1-(4-fluorophenyl)-1H-pyrazol-4-amine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86257708 | HCID 86257708 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | 1-(4-fluorophenyl)-1H-pyrazol-4-amine | HCID 43531715 | 96.2% |
Reaction Steps
A mixture of 1-(4-fluorophenyl)-4-nitropyrazole (0.820 g, 3.96 mmol) and 10% Pd/C (0.133 g, 50% wet by wt) in EtOH (50 mL) was fitted onto a Parr apparatus and agitated under H2 at 40 psi for 40 min. The reaction mixture was then filtered through filter paper. The filtrate was collected and concentrated in vacuo to give 1-(4-fluorophenyl)pyrazol-4-amine as an oil (0.675 g, 96%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09169248B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-a18390c029154e59af9a3eb968c86735 |
| Source note | uspto-grants-2015_10 |