4-Fluoro-2-methylbenzaldehyde → 1-Bromomethyl-4-methanesulfonyl-2-methyl-benzene

HRID 1754508Notes

Reaction equation

HRID 1754508 reaction equation
[Br:1][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([S:9]([CH3:12])(=[O:11])=[O:10])=[C:5](F)[CH:4]=1.F[C:15]1C=CC(C=O)=C(C)C=1>>[Br:1][CH2:2][C:3]1[CH:8]=[CH:7][C:6]([S:9]([CH3:12])(=[O:11])=[O:10])=[CH:5][C:4]=1[CH3:15]

Participants

3

Reactant 2

HCID 27832174-Fluoro-2-methylbenzaldehydeHCID 672190653-Fluoro-4-(methylsulphonyl)benzyl bromide

Product 1

HCID 672191581-Bromomethyl-4-methanesulfonyl-2-methyl-benzene

Procedure

The titled compound is prepared analogously to 4-bromomethyl-2-fluoro-1-methanesulfonyl-benzene by replacing 3,4-difluorobenzaldehyde with 4-fluoro-2-methylbenzaldehyde.

Sources & evidence

ORD record
ord-151afbe0e3084ed0ab3575f7bbd0268a
Source dataset
uspto-grants-2015_10
Patent number
US09169251B2

Reaction notes

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