1-Chloro-5-fluoro-2-methoxy-4-nitrobenzene → 942199-58-8

HRID 1754524Notes

Reaction equation

HRID 1754524 reaction equation
C(C1C=CC([S:9]([Cl:12])(=[O:11])=[O:10])=CC=1OCC)#N.[Cl:16][C:17]1[CH:22]=[C:21]([F:23])[C:20]([N+]([O-])=O)=[CH:19][C:18]=1[O:27][CH3:28]>>[Cl:16][C:17]1[C:18]([O:27][CH3:28])=[CH:19][C:20]([S:9]([Cl:12])(=[O:11])=[O:10])=[C:21]([F:23])[CH:22]=1

Participants

3

Reactant 2

HCID 27792951-Chloro-5-fluoro-2-methoxy-4-nitrobenzeneHCID 552808794-Cyano-3-ethoxybenzene-1-sulfonyl chloride2×

Product 1

HCID 84806054942199-58-8

Procedure

The titled compound was prepared analogously to 4-cyano-3-ethoxy-benzenesulfonyl chloride (Intermediate 127c) by replacing 2-ethoxy-4-nitro-benzonitrile with 1-chloro-5-fluoro-2-methoxy-4-nitro-benzene.

Sources & evidence

ORD record
ord-9be9407e298b4754a924a0ed2a03cde6
Source dataset
uspto-grants-2015_10
Patent number
US09169251B2

Reaction notes

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