6-Chloro-m-anisidine → 2-Chloro-5-methoxybenzene-1-sulfonyl chloride

HRID 1754527Notes

Reaction equation

HRID 1754527 reaction equation
F[C:2]1[CH:7]=[CH:6][C:5]([S:8]([Cl:11])(=[O:10])=[O:9])=[CH:4][C:3]=1[O:12][CH3:13].[Cl:14]C1C=CC(OC)=CC=1N>>[Cl:14][C:6]1[CH:7]=[CH:2][C:3]([O:12][CH3:13])=[CH:4][C:5]=1[S:8]([Cl:11])(=[O:10])=[O:9]

Participants

3

Reactant 2

HCID 754606-Chloro-m-anisidineHCID 27834084-Fluoro-3-methoxybenzenesulfonyl chloride2×

Product 1

HCID 220335362-Chloro-5-methoxybenzene-1-sulfonyl chloride

Procedure

The titled compound is prepared analogously to 4-fluoro-3-methoxy-benzenesulfonyl chloride (Intermediate 102a) by replacing 4-fluoro-3-methoxyaniline with 2-chloro-5-methoxy-phenylamine.

Sources & evidence

ORD record
ord-a0851f4a19b847fba44f6b1d0675e3a7
Source dataset
uspto-grants-2015_10
Patent number
US09169251B2

Reaction notes

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