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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1754531Generated: October 28, 2026

3-Chloro-4-(trifluoromethyl)aniline → 3-Chloro-4-(trifluoromethyl)benzene-1-sulfonyl chloride

https://huagongshe.com/reaction/1754531

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-Chloro-4-(trifluoromethyl)anilineHCID 67962—
Reactant4-Fluoro-3-methoxybenzenesulfonyl chlorideHCID 2783408—
Product3-Chloro-4-(trifluoromethyl)benzene-1-sulfonyl chlorideHCID 22148755—

Reaction Steps

The titled compound is prepared analogously to 4-fluoro-3-methoxy-benzenesulfonyl chloride (Intermediate 102a) by replacing 4-fluoro-3-methoxyaniline with 3-chloro-4-trifluoromethyl-phenylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09169251B2
Source datasetuspto-grants-2015_10
ORD IDord-c052dd80782342dd9d4aa89962f22503
Source noteuspto-grants-2015_10