1,2-Benzenedicarbonitrile, 4-amino- → 4-(chlorosulfonyl)phthalonitrile

HRID 1754535Notes

Reaction equation

HRID 1754535 reaction equation
FC1C=CC([S:8]([Cl:11])(=[O:10])=[O:9])=CC=1OC.N[C:15]1[CH:16]=[C:17]([C:23]#[N:24])[C:18](=[CH:21][CH:22]=1)[C:19]#[N:20]>>[C:23]([C:17]1[CH:16]=[C:15]([S:8]([Cl:11])(=[O:10])=[O:9])[CH:22]=[CH:21][C:18]=1[C:19]#[N:20])#[N:24]

Participants

3

Reactant 2

HCID 925291,2-Benzenedicarbonitrile, 4-amino-HCID 27834084-Fluoro-3-methoxybenzenesulfonyl chloride2×

Product 1

HCID 111954984-(chlorosulfonyl)phthalonitrile

Procedure

The titled compound is prepared analogously to 4-fluoro-3-methoxy-benzenesulfonyl chloride (Intermediate 102a) by replacing 4-fluoro-3-methoxyaniline with 4-amino-phthalonitrile.

Sources & evidence

ORD record
ord-13bfcca64ad1402a83392bdb2ceca88e
Source dataset
uspto-grants-2015_10
Patent number
US09169251B2

Reaction notes

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