HCID 57595758, compound → HCID 59593333, compound

HRID 1754634Notes

Reaction equation

HRID 1754634 reaction equation
[CH2:1]([NH:5][C:6]1[N:11]=[CH:10][C:9]([C:12]([C:14]2[C:22]3[C:17](=[N:18][CH:19]=[CH:20][CH:21]=3)[NH:16][CH:15]=2)=O)=[CH:8][CH:7]=1)[CH:2]([CH3:4])[CH3:3].C1(CNC2N=CC(C(C3C4C(=NC=CC=4)NC=3)=O)=CC=2)CC1>>[CH:2]1([CH2:1][NH:5][C:6]2[CH:7]=[CH:8][C:9]([CH2:12][C:14]3[C:22]4[C:17](=[N:18][CH:19]=[CH:20][CH:21]=4)[NH:16][CH:15]=3)=[CH:10][N:11]=2)[CH2:4][CH2:3]1

Participants

3

Reactant 2

HCID 57595758HCID 57595758, compoundHCID 59593273HCID 59593273, compound

Product 1

HCID 59593333HCID 59593333, compound

Procedure

was prepared following the protocol of Scheme 8, substituting (6-Isobutylamino-pyridin-3-yl)-(1H-pyrrolo[2,3-b]pyridin-3-yl)-methanone P-0025 with [6-(Cyclopropylmethyl-amino)-pyridin-3-yl]-(1H-pyrrolo[2,3-b]pyridin-3-yl)-methanone P-0030 (prepared as described in Example 5). MS (ESI) [M+H+]+=279.

Workup

  1. customwas prepared
  2. custom(prepared as described in Example 5)

Sources & evidence

ORD record
ord-d4b881507bb24f139de56384d0422e64
Source dataset
uspto-grants-2015_10
Patent number
US09169250B2

Reaction notes

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