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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1754656Generated: October 30, 2026

tert-Butyldimethylsilyl chloride → 1H-Pyrrolo[2,3-B]pyridine, 1-[(1,1-dimethylethyl)dimethylsilyl]-3-iodo-

https://huagongshe.com/reaction/1754656

Reaction equation

Participants

RoleNameHCIDCharge
Reactanttert-Butyldimethylsilyl chlorideHCID 28928—
ReactantTriisopropylsilyl chlorideHCID 139400—
Reactant3-Iodo-7-azaindoleHCID 5377078—
Product1H-Pyrrolo[2,3-B]pyridine, 1-[(1,1-dimethylethyl)dimethylsilyl]-3-iodo-HCID 49758960—

Reaction Steps

was prepared following the protocol of Scheme 20 Step 2, substituting 1H-Pyrrolo[2,3-b]pyridine-3-carbaldehyde 46 with 3-iodo-1H-pyrrolo[2,3-b]pyridine and triisopropylsilyl chloride with tert-Butyl-dimethyl-silyl chloride.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09169250B2
Source datasetuspto-grants-2015_10
ORD IDord-d116cef1106847df98671f62f07e9639
Source noteuspto-grants-2015_10