Iodoacetamide → HCID 71677836, compound

Participants

Reaction Steps

A solution of 1.850 g (10 mmol) iodoacetamide and 1.152 g (10 mmol) tetrahydro[1,3]oxazolo[2,3-b][1,3]oxazole in 20 ml of methanol was refluxed for 1 hour. The solvent was then removed under reduced pressure and the residue was allowed to crystallize overnight. The precipitate was filtered off, washed twice with dichloromethane and dried. 2.041 g (68.0%) of white crystalline product was obtained.

Provenance & Evidence