HuagongsheHuagongshe Chemistry Print Report · For research reference only
Acetyl chloride → HCID 90032984, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Acetyl chloride | HCID 6367 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | HCID 90022235 | HCID 90022235 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 90032984 | HCID 90032984 | — |
Reaction Steps
To an-ice cooled solution of (±)-2-amino-4-(5-chloro-2-ethoxycarbonylmethoxy-phenyl)-6,7-dihydro-4H-thiazolo[5,4-c]pyridine-5-carboxylic acid benzyl ester (50 mg, 100 μmol, 1 eq.) and NEt3 (69 μL, 500 μmol, 5 eq.) in DCM (1 mL), acetyl chloride (14 μL, 200 μmol, 2 eq.)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09169270B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-27b79870ffec48dda1160a383dfaa2c0 |
| Source note | uspto-grants-2015_10 |