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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1754850Generated: October 28, 2026

Acetyl chloride → HCID 90032984, compound

https://huagongshe.com/reaction/1754850

Reaction equation

Participants

RoleNameHCIDCharge
ReactantAcetyl chlorideHCID 6367—
ReactantTriethylamineHCID 8471—
ReactantHCID 90022235HCID 90022235—
SolventDichloromethaneHCID 6344—
ProductHCID 90032984HCID 90032984—

Reaction Steps

To an-ice cooled solution of (±)-2-amino-4-(5-chloro-2-ethoxycarbonylmethoxy-phenyl)-6,7-dihydro-4H-thiazolo[5,4-c]pyridine-5-carboxylic acid benzyl ester (50 mg, 100 μmol, 1 eq.) and NEt3 (69 μL, 500 μmol, 5 eq.) in DCM (1 mL), acetyl chloride (14 μL, 200 μmol, 2 eq.)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS09169270B2
Source datasetuspto-grants-2015_10
ORD IDord-27b79870ffec48dda1160a383dfaa2c0
Source noteuspto-grants-2015_10