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HRID1755450

反应详情

EQUATION

反应方程式

HRID 1755450 的结构方程式

REACTANTS

反应物

2
结构：COc1ccc(C[C@H]2NC[C@H](O)[C@H]2OC(C)=O)cc1
HCID253602

Anisomycin

C14H19NO4

结构：CO.N
HCID21705897

未命名化合物

PRODUCTS

生成物

1
结构：COc1ccc(C[C@H]2NC[C@H](O)[C@H]2O)cc1
HCID11790817

Deacetylanisomycin

C12H17NO3

PROCEDURE

实验过程

To a 500 mL round bottom flask containing solid (2R,3S,4S)-4-hydroxy-2-(4-methoxybenzyl)pyrrolidin-3-yl acetate (513.3 mg, 1.935 mmol) and a magnetic stir bar is added 2M NH3/MeOH (200 mL, 400 mmol). The resulting light tan solution is capped and stirred at room temp for 5 days. The solvent is removed in vacuo to give the title compound that is used directly “as is” in the next step. LC/MS (Condition A): ret. T=1.42 min, (M+H)+ 224.11.

WORKUP

后处理

  1. customThe resulting light tan solution is capped
  2. customThe solvent is removed in vacuo