HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methanol → HCID 67262995, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methanol | HCID 887 | — |
| Reactant | Ethylamine | HCID 6341 | — |
| Reactant | Trolox | HCID 40634 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Product | HCID 67262995 | HCID 67262995 | — |
Reaction Steps
Following the amide coupling procedure described in protocol A, 500 mg 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (2.00 mmol), 356 mg CDI (2.20 mmol) and 1.1 mL of a 2.0 solution of ethylamine in methanol (2.2 mmol) produced 334 mg of as N-ethyl-6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxamide as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09169196B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-055774f92aba4d4098f67d53bdf48753 |
| Source note | uspto-grants-2015_10 |