HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trolox → HCID 67263055, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trolox | HCID 40634 | — |
| Reactant | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| Reactant | Cyclopropylamine | HCID 69828 | — |
| Product | HCID 67263055 | HCID 67263055 | 39.2% |
Reaction Steps
Following the amide coupling procedure described in protocol A, 500 mg 6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxylic acid (2.00 mmol), 357 mg CDI (2.00 mmol) and 126 mg cyclopropylamine (2.2 mmol) produced 227 mg of N-cyclopropyl-6-hydroxy-2,5,7,8-tetramethylchroman-2-carboxamide as a pale brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US09169196B2 |
| Source dataset | uspto-grants-2015_10 |
| ORD ID | ord-4a6b4af597fe4b279f6d8b76cc1516af |
| Source note | uspto-grants-2015_10 |