HuagongsheHuagongshe Chemistry Print Report · For research reference only
Chloral Hydrate → HCID 73668067, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Chloral Hydrate | HCID 2707 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | N-[(6-Chloro-3-pyridinyl)methyl]-N,N′-dimethyl-2-nitro-1,1-ethenediamine | HCID 85054604 | — |
| Solvent | Acetonitrile | HCID 6342 | — |
| Product | HCID 73668067 | HCID 73668067 | — |
Reaction Steps
Chloral hydrate (0.40 g) was added slowly in 40 minutes to a mixture of 1-[N-(6-chloro-3-pyridylmethyl)-N-methylamino]-1-methylamino-2-nitroethylene (0.26 g), triethylamine (0.1 g) and acetonitrile (3 ml). The mixture was stirred at room temperature for 21 hours and under refluxing for 9 hours. The resultant crystals were collected by filtration to give 1,1,1-trichloro-4-[N-(6-chloro-3-pyridylmethyl)-N-methylamino]-4-methylamino-3-nitro-3-buten-2-ol (Compound No. 11) (0.23 g) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05438065 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-1ff890c3c78b4785bb77c8a88bfd7899 |
| Source note | uspto-grants-1995_08 |