HuagongsheHuagongshe Chemistry Print Report · For research reference only
Triethylamine → HCID 54437313, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1) | HCID 466102 | — |
| Reactant | HCID 54196997 | HCID 54196997 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 54437313 | HCID 54437313 | — |
Reaction Steps
A solution of the tetrahydropyranyl ether of Step 6 (1.552 g, 2.83 mmol) and pyridinium p-toluenesulfonate (176 mg, 0.25 equiv.) in 15 mL of MeOH was stirred at room temperature for 2 days. Triethylamine (100 μL, 1 equiv.) was then added, the solvent evaporated, and the residue purified by flash chromotography on silica with EtOAc:toluene 20:80. Yield 1.189 g, 91%.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05438141 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-1e0a8c8b9d54472bb2d96fecc08d3190 |
| Source note | uspto-grants-1995_08 |