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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1755785Generated: October 26, 2026

Thiocyanic Acid → 5-Hydroxymethyl-1-(5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)-1,3-dihydroimidazole-2-thione

https://huagongshe.com/reaction/1755785

Reaction equation

Participants

RoleNameHCIDCharge
ReactantThiocyanic AcidHCID 781—
Reactant1,1-Dihydroxypropan-2-oneHCID 13180982—
Reactant5,7-Difluoro-1,2,3,4-tetrahydronaphthalen-2-ylamineHCID 19699423—
Product5-Hydroxymethyl-1-(5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)-1,3-dihydroimidazole-2-thioneHCID 19699302—

Reaction Steps

reacting 5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-ylamine with thiocyanic acid and dihydroxyacetone to give 5-hydroxymethyl-1-(5,7-difluoro-1,2,3,4-tetrahydronaphthalen-2-yl)-1,3-dihydroimidazole-2-thione and

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05438150
Source datasetuspto-grants-1995_08
ORD IDord-15cf4d9f9fb3474198861d4893672bb0
Source noteuspto-grants-1995_08