HuagongsheHuagongshe Chemistry Print Report · For research reference only
Allyl bromide → N-allyl-D-alanine t-butyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Allyl bromide | HCID 7841 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | tert-butyl (2R)-2-aminopropanoate | HCID 7359212 | — |
| Solvent | Toluene | HCID 1140 | — |
| Product | N-allyl-D-alanine t-butyl ester | HCID 54332184 | — |
Reaction Steps
D-Alanine t-butylester (68) is treated with one equivalent allyl bromide and one equivalent of triethylamine in toluene under reflux. The solvent is evaporated and the product is purified by flash chromatography on silica gel to give (69).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05438118 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-48efffad11d94dafa55ea06d132ab9b7 |
| Source note | uspto-grants-1995_08 |