Formic Acid → Glyoxylic Acid

HRID 1755972Notes

Reaction equation

HRID 1755972 reaction equation
[C:1]([O-:5])(=[O:4])[CH2:2][OH:3].[CH:6]([OH:8])=[O:7]>>[C:1]([OH:5])(=[O:4])[CH:2]=[O:3].[C:1]([OH:5])(=[O:4])[C:6]([OH:8])=[O:7]

Participants

4

Reactant 2

HCID 284Formic AcidHCID 5460308Hydroxyacetate

Product 2

HCID 760Glyoxylic AcidHCID 971Oxalic Acid

Procedure

The reaction described in Example 4 was repeated, except that the same amounts of soluble, unimmobilized glycolate oxidase and catalase were added to the reaction mixture. After 4 hours, the yields of glyoxylic acid, oxalic acid, and formic acid were 43%, 0%, and 0%, respectively, with a 46% conversion of glycolic acid. The final activities of glycolate oxidase and catalase were <2% and 82% of their initial values, respectively, and no further reaction was observed at longer reaction times.

Workup

  1. additionwere added to the reaction mixture

Sources & evidence

ORD record
ord-4abf5ca2e14d47bc91e953f21d023f25
Source dataset
uspto-grants-1995_08
Patent number
US05439813

Reaction notes

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