HuagongsheHuagongshe Chemistry Print Report · For research reference only
Phenethyl bromide → 3-Chloro-2-methyl-7-(2-phenylethyl)pyrrolo[2,3-b]pyridine hydrobromide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Phenethyl bromide | HCID 7666 | — |
| Reactant | Ethyl Acetate | HCID 8857 | — |
| Reactant | 3-Chloro-2-methyl-1H-pyrrolo[2,3-b]pyridine | HCID 19392593 | — |
| Solvent | Dimethylformamide | HCID 6228 | — |
| Product | 3-Chloro-2-methyl-7-(2-phenylethyl)pyrrolo[2,3-b]pyridine hydrobromide | HCID 21743847 | 50.2% |
Reaction Steps
A solution of 28.4 mg (0.17 mmol) of 3-chloro-2-methyl pyrrolo [2,3-b]pyridine and 36 mg (0.2mmol) of (2bromoethyl)benzene in 0.4 ml of dimethylformamid was heated at 80° C. for 20 h. The solvent was evaporated. The solid that formed was treated with ethyl acetate and isolated by filtration to give 30 mg (50%) of 3 -chloro-2-methyl-7-(2-phenylethyl)pyrrolo[2,3-b]pyridine hydrobromide.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05439917 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-34eb9f3209d4462ab697e77e8b757efb |
| Source note | uspto-grants-1995_08 |