HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 2,3-Dimethyl-5-methylthio-7-phenacylpyrrolo[2,3-b]pyridine
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | 2-Chloroacetophenone | HCID 10757 | — |
| Reactant | 2,3-Dimethyl-6-mehylthiopyrrolo[2,3-b]pyridine | HCID 19392610 | — |
| Reactant | 2,3-Dimethyl-5-methylthiopyrrolo[2,3-b]pyridine | HCID 19916823 | — |
| Product | 2,3-Dimethyl-5-methylthio-7-phenacylpyrrolo[2,3-b]pyridine | HCID 19916797 | 63% |
Reaction Steps
The title compound was prepared on a 0.6 mmol scale from 2,3-dimethyl-5-methylthiopyrrolo[2,3-b]pyridine (prepared according to the procedure described for 2,3-dimethyl-6-methylthio-pyrrolo[2,3-b]pyridine) and phenacyl chloride as described in Example 43 yielding 140 mg (63%) pure title compound as the hydrochloride.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05439917 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-3d14531c529746d9b83f1643dae5288f |
| Source note | uspto-grants-1995_08 |