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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1756093Generated: October 28, 2026

2-Chloro-1-(2,4-difluorophenyl)ethanone → HCID 21743851, compound

https://huagongshe.com/reaction/1756093

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloro-1-(2,4-difluorophenyl)ethanoneHCID 588083—
ReactantHCID 19916787HCID 19916787—
SolventAcetonitrileHCID 6342—
ProductHCID 21743851HCID 21743851—

Reaction Steps

The title compound was prepared from 3-(cyanomethyl)-5-fluoro-2-methylpyrrolo[2,3-b]pyridine (10 mg, 0.053 mmol) and 2,4-difluorophenacyl chloride (128 mg, 0.67 mmol) in acetonitrile (0.2 ml) in the same fashion as described in example 71; yield 16 mg (80%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05439917
Source datasetuspto-grants-1995_08
ORD IDord-481411bc9fe94cecb4dc7151e1992b7c
Source noteuspto-grants-1995_08