HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-(Hydroxymethyl)furfural → 2-Furanmethanol, 5-(dimethoxymethyl)-
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-(Hydroxymethyl)furfural | HCID 237332 | — |
| Reactant | Benzenesulfonic acid, 4-methyl-, compd. with pyridine (1:1) | HCID 466102 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | Methylorthoformate | HCID 53629101 | — |
| Solvent | Methanol | HCID 887 | — |
| Solvent | Water | HCID 962 | — |
| Solvent | Diethyl Ether | HCID 3283 | — |
| Product | 2-Furanmethanol, 5-(dimethoxymethyl)- | HCID 588127 | — |
Reaction Steps
16.8 g of 5-hydroxymethyl-2-furaldehyde was dissolved in 70 ml of methanol, and 14.7 ml of methyl orthoformate and 170 mg of pyridinium p-toluenesulfonate were added. After the mixture was stirred at room temperature for 2 hours, 350 mg of sodium bicarbonate was added. The solution was stirred at room temperature for 30 minutes, and then ethyl ether and water were added. The organic layer separated was worked up in a customary manner to give 21.6 g of 5-hydroxymethyl-2-furaldehyde dimethylacetal as a pale brown oil.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05439932 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-d53e4499a45a420f95c6b0752a5c3cd1 |
| Source note | uspto-grants-1995_08 |