Sodium Hydroxide → HCID 19966473, compound

HRID 1756347Notes

Reaction equation

HRID 1756347 reaction equation
[OH:1][CH:2]([CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])/[CH:3]=[CH:4]/[C:5]1[N:10]=[C:9]([CH2:11][CH:12]2[O:16][C:15](=[O:17])[CH2:14][CH2:13]2)[CH:8]=[CH:7][CH:6]=1.[OH-:26].[Na+]>CO>[OH:16][CH:12]([CH2:11][C:9]1[CH:8]=[CH:7][CH:6]=[C:5](/[CH:4]=[CH:3]/[CH:2]([OH:1])[CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[N:10]=1)[CH2:13][CH2:14][C:15]([OH:26])=[O:17]

Participants

4

Reactant 2

HCID 14798Sodium HydroxideHCID 19966483HCID 19966483, compound

Product 1

HCID 19966473HCID 19966473, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

Under the conditions of example 2, 30 mg of 5-{6-[(1E)(3RS)-3-hydroxy-1-undecenyl]-2-pyridyl-methyl)-tetrahydrofuran-2-one in 2 ml of methanol is saponified with 1 ml of 1 n sodium hydroxide solution and worked up. 20 mg of the title compound is obtained as oil.

Sources & evidence

ORD record
ord-8acaa946eddd49fa987aa0eecac0fadf
Source dataset
uspto-grants-1995_08
Patent number
US05440044

Reaction notes

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