Methyl 4-aminobenzoate → HCID 54447533, compound

HRID 1756438Notes

Reaction equation

HRID 1756438 reaction equation
[C:1]12([C:11]3[CH:12]=[C:13]([CH2:19][C:20](Cl)=[O:21])[CH:14]=[CH:15][C:16]=3[O:17][CH3:18])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2.[NH2:23][C:24]1[CH:33]=[CH:32][C:27]([C:28]([O:30][CH3:31])=[O:29])=[CH:26][CH:25]=1>>[C:1]12([C:11]3[CH:12]=[C:13]([CH2:19][C:20]([NH:23][C:24]4[CH:25]=[CH:26][C:27]([C:28]([O:30][CH3:31])=[O:29])=[CH:32][CH:33]=4)=[O:21])[CH:14]=[CH:15][C:16]=3[O:17][CH3:18])[CH2:10][CH:5]3[CH2:6][CH:7]([CH2:9][CH:3]([CH2:4]3)[CH2:2]1)[CH2:8]2

Participants

3

Reactant 2

HCID 12082Methyl 4-aminobenzoateHCID 21474496HCID 21474496, compound

Product 1

HCID 54447533HCID 54447533, compound

Procedure

In a manner similar to Example 1(d), by reaction of 3.8 g (11.9 mmol) of 3-(1-adamantyl)-4-methoxyphenylacetyl chloride with 1.81 g (12 mmol) of methyl 4-aminobenzoate, 3.2 g (63%) of the expected methyl ester, melting point 146°-147° C., are obtained.

Workup

  1. customare obtained

Sources & evidence

ORD record
ord-53c1dc4d32c247fda2efa18a08d41c15
Source dataset
uspto-grants-1995_08
Patent number
US05439925

Reaction notes

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