5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-amine → HCID 21474576, compound

HRID 1756440Notes

Reaction equation

HRID 1756440 reaction equation
[CH3:1][C:2]1([CH3:15])[CH2:11][CH2:10][C:9]([CH3:13])([CH3:12])[C:8]2[CH:7]=[C:6]([NH2:14])[CH:5]=[CH:4][C:3]1=2.[CH2:16]([O:19][C:20]([C:22]1[CH:27]=[CH:26][C:25]([CH2:28][C:29](O)=[O:30])=[CH:24][CH:23]=1)=[O:21])[CH:17]=[CH2:18]>>[CH3:1][C:2]1([CH3:15])[CH2:11][CH2:10][C:9]([CH3:13])([CH3:12])[C:8]2[CH:7]=[C:6]([NH:14][C:29]([CH2:28][C:25]3[CH:26]=[CH:27][C:22]([C:20]([O:19][CH2:16][CH:17]=[CH2:18])=[O:21])=[CH:23][CH:24]=3)=[O:30])[CH:5]=[CH:4][C:3]1=2

Participants

3

Reactant 2

HCID 114697605,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-amineHCID 21474575HCID 21474575, compound

Product 1

HCID 21474576HCID 21474576, compound

Procedure

In a manner similar to Example 4(c), by reaction of 2 g (10 mmol) of 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl -2-naphthylamine with 2.2 g (10 mmol) of 4-(allyloxycarbonyl)phenylacetic acid, 3.7 g (92%) of the expected ester, melting point 49°-50° C., are obtained.

Workup

  1. customare obtained

Sources & evidence

ORD record
ord-e870025fd7bd46a995de2c31838ada8d
Source dataset
uspto-grants-1995_08
Patent number
US05439925

Reaction notes

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