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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1756443Generated: October 27, 2026

Methyl 4-methylaminobenzoate → Methyl 4-(N-methyl-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylacetamido)benzoate

https://huagongshe.com/reaction/1756443

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 4-methylaminobenzoateHCID 140375—
Reactant2-(5,5,8,8-Tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)acetic acidHCID 18177932—
ProductMethyl 4-(N-methyl-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylacetamido)benzoateHCID 5423783254%

Reaction Steps

In a manner similar to Example 4(c), by reaction of 2.46 g (10 mmol) of 5,6,7,8-tetrahydro-5,5,8,8-tetramethyl -2-naphthylacetic acid with 1.65 g (10 mmol) of methyl 4-methylaminobenzoate, 2.1 g (54%) of the expected product are obtained in the form of a colorless oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05439925
Source datasetuspto-grants-1995_08
ORD IDord-3716ef43d9a0404eb315b81aaf1fec5e
Source noteuspto-grants-1995_08