Methyl 4-aminobenzoate → HCID 54449628, compound

HRID 1756450Notes

Reaction equation

HRID 1756450 reaction equation
[CH2:1]=[C:2]([C:6]1[CH:15]=[CH:14][C:13]2[C:12]([CH3:17])([CH3:16])[CH2:11][CH2:10][C:9]([CH3:19])([CH3:18])[C:8]=2[CH:7]=1)[C:3](O)=[O:4].[NH2:20][C:21]1[CH:30]=[CH:29][C:24]([C:25]([O:27][CH3:28])=[O:26])=[CH:23][CH:22]=1>>[CH2:1]=[C:2]([C:6]1[CH:15]=[CH:14][C:13]2[C:12]([CH3:17])([CH3:16])[CH2:11][CH2:10][C:9]([CH3:19])([CH3:18])[C:8]=2[CH:7]=1)[C:3]([NH:20][C:21]1[CH:22]=[CH:23][C:24]([C:25]([O:27][CH3:28])=[O:26])=[CH:29][CH:30]=1)=[O:4]

Participants

3

Reactant 2

HCID 12082Methyl 4-aminobenzoateHCID 17867591HCID 17867591, compound

Product 1

HCID 54449628HCID 54449628, compound

Procedure

In a manner similar to Example 4(c), by reaction of 4.6 g (18 mmol) of α-methylene-5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthylacetic acid with 2.7 g (18 mmol) of methyl 4-aminobenzoate, 2.4 g (34%) of the expected ester are obtained in the form of a colorless oil.

Workup

  1. customare obtained in the form of a colorless oil

Sources & evidence

ORD record
ord-5f0e25df50c34a8783a437c0153be926
Source dataset
uspto-grants-1995_08
Patent number
US05439925

Reaction notes

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