8-Nitroquinoline-2-carboxylic acid → 5-Nitro-3-isoquinolinecarboxylic acid

HRID 1756508Notes

Reaction equation

HRID 1756508 reaction equation
C(C1N=CC2C(C=1)=CC=CC=2)(O)=O.[C:14]([C:17]1[CH:26]=[CH:25][C:24]2[C:19](=[C:20]([N+:27]([O-:29])=[O:28])[CH:21]=[CH:22][CH:23]=2)[N:18]=1)([OH:16])=[O:15]>>[C:14]([C:17]1[N:18]=[CH:19][C:24]2[C:25]([CH:26]=1)=[C:20]([N+:27]([O-:29])=[O:28])[CH:21]=[CH:22][CH:23]=2)([OH:16])=[O:15]

Participants

3

Reactant 2

HCID 850758-Nitroquinoline-2-carboxylic acidHCID 124656Isoquinoline-3-carboxylic acid

Product 1

HCID 193906095-Nitro-3-isoquinolinecarboxylic acid

Procedure

3-Carboxy-5-nitroisoquinoline was prepared from 3-carboxyisoquinoline using a method similar to that used for the preparation of 2-carboxy-8-nitroquinoline in example 10 (Yield: 93%).

Sources & evidence

ORD record
ord-22eb5018b77440a1be5427abb54b9713
Source dataset
uspto-grants-1995_08
Patent number
US05441949

Reaction notes

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