HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hexane → HCID 15341008, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hexane | HCID 8058 | — |
| Reactant | NSC65652 | HCID 248486 | — |
| Reactant | Lithium | HCID 3028194 | — |
| Reactant | 8-chlorodibenz[b,f][1,4]oxazepin-10(11H)carbonyl chloride | HCID 14975983 | — |
| Reactant | Butyllithium | HCID 178418339 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | HCID 15341008 | HCID 15341008 | 40.9% |
Reaction Steps
By the procedure described in Example 11, 3-(4-pyridylmethylamino)-1-propanol (1.0 g, 3.4 mmol) in 30 mL of THF was converted to its lithium salt with 1.6M n-butyllithium in hexane (2.1 mL, 3.4 mmol) and reacted with the product of Example 2 (1.0 g, 3.4 mmol) to yield 590 mg of the title product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05441950 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-3fffa10f6d4f4588bae7e4792eac269c |
| Source note | uspto-grants-1995_08 |