HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isatin → HCID 478656, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isatin | HCID 7054 | — |
| Reactant | 2-Aminonicotinic acid | HCID 72930 | — |
| Reactant | 5,7-Difluoro-1H-indole-2,3-dione | HCID 16794671 | — |
| Product | HCID 478656 | HCID 478656 | 4.7% |
Reaction Steps
Using the procedure in Example 56 and substituting 2-aminobenzoic acid for 2-aminonicotinic acid and 5,7-difluoroisatin from Example 3 for isatin gave the title compound in 4.7% yield: mp 287°-290° C,; 1H NMR (300 MHz, CDCl3) δ 8.47 (d, 1H) 8.02 (d, 1H) 7.84-7.92 (m, 1H) 7.66-7.76 (m, 1H) 7.48-7.54 (m, 1H) 7.30-7.40 (m, 1H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05441955 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-49995c01cdf740de84878c2b86594f10 |
| Source note | uspto-grants-1995_08 |