5-Fluoroisatin → HCID 19390716, compound

HRID 1756589Notes

Reaction equation

HRID 1756589 reaction equation
[F:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[NH:7][C:6](=O)[C:5]2=[O:12].F[C:14]1C=[C:18]2C(O[C:22](=[O:24])[NH:23][C:17]2=[CH:16][CH:15]=1)=O.FC1C=C2[NH:35]C(=O)OC(=O)C2=CC=1>>[F:1][C:2]1[CH:3]=[C:4]2[C:8](=[CH:9][CH:10]=1)[N:7]=[C:6]1[C:5](=[O:12])[C:16]3[C:17]([N:23]1[C:22]2=[O:24])=[CH:18][N:35]=[CH:14][CH:15]=3

Participants

4

Reactant 3

HCID 2365665-FluoroisatinHCID 2885605-Fluoroisatoic anhydrideHCID 100581387-Fluoroisatoic anhydride

Product 1

HCID 19390716HCID 19390716, compound

Procedure

Using the procedure in Example 36 and substituting 6-azaisatin (Example 9, J. Parrick et al., Tetrahedron Lett. 25:3099, 1984) for 5-fluoroisatin and 5-fluoroisatoic anhydride for 4-fluoroisatoic anhydride gives the title compound.

Sources & evidence

ORD record
ord-8f7ec9bd12714e7dafd43d85cdec0cd4
Source dataset
uspto-grants-1995_08
Patent number
US05441955

Reaction notes

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