2-(Trimethylstannyl)furan → 2-Amino-1-[4-(2-furyl)phenyl]benzimidazole
Reaction equation
[NH2:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][C:10](I)=[CH:9][CH:8]=2)[C:5]2[CH:14]=[CH:15][CH:16]=[CH:17][C:4]=2[N:3]=1.C[Sn](C)(C)[C:20]1[O:21][CH:22]=[CH:23][CH:24]=1>>[NH2:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][C:10]([C:20]3[O:21][CH:22]=[CH:23][CH:24]=3)=[CH:9][CH:8]=2)[C:5]2[CH:14]=[CH:15][CH:16]=[CH:17][C:4]=2[N:3]=1Participants
3
Procedure
2-Amino-1-[4-(2-furyl)phenyl]benzimidazole was prepared from 1 -(2-amino-1-benzimidazolyl)-4-iodobenzene and 2-trimethylstannylfuran according to method C, mp 210°-212° C.
Sources & evidence
- ORD record
- ord-6f12177e5e2b44ea9870271008801659
- Source dataset
- uspto-grants-1995_08
- Patent number
- US05441969
Reaction notes
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