HCID 19390950, compound → 2-Amino-1-[3-(3-methoxymethyl-2-furyl)phenyl]benzimidazole

HRID 1756645Notes

Reaction equation

HRID 1756645 reaction equation
[NH2:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][CH:10]=[C:9](I)[CH:8]=2)[C:5]2[CH:14]=[CH:15][CH:16]=[CH:17][C:4]=2[N:3]=1.[CH3:18][O:19][CH2:20][C:21]1[CH:25]=[CH:24][O:23][C:22]=1[Sn](C)(C)C>>[NH2:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][CH:10]=[C:9]([C:22]3[O:23][CH:24]=[CH:25][C:21]=3[CH2:20][O:19][CH3:18])[CH:8]=2)[C:5]2[CH:14]=[CH:15][CH:16]=[CH:17][C:4]=2[N:3]=1

Participants

3

Reactant 2

HCID 19390950HCID 19390950, compoundHCID 193909601-(3-Iodophenyl)-1H-benzimidazol-2-amine

Product 1

HCID 193909772-Amino-1-[3-(3-methoxymethyl-2-furyl)phenyl]benzimidazole

Procedure

2-Amino-1-[3-(3-methoxymethyl-2-furyl)phenyl]benzimidazole was prepared from 1-(2-amino-1-benzimidazolyl)-3-iodobenzene and 3-methoxymethyl-2-trimethylstannylfuran by method C. mp 134°-136° C.

Sources & evidence

ORD record
ord-054769c398dd4852ac094c1e40835715
Source dataset
uspto-grants-1995_08
Patent number
US05441969

Reaction notes

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