4-Bromo-1,3,5-trimethylpyrazole → 2-Amino-1-[3-(1,3,5-trimethyl-4-pyrazolyl)phenyl]benzimidazole

HRID 1756646Notes

Reaction equation

HRID 1756646 reaction equation
[NH2:1][C:2]1[N:6]([C:7]2[CH:8]=[C:9](B3OCCCO3)[CH:10]=[CH:11][CH:12]=2)[C:5]2[CH:19]=[CH:20][CH:21]=[CH:22][C:4]=2[N:3]=1.Br[C:24]1[C:25]([CH3:31])=[N:26][N:27]([CH3:30])[C:28]=1[CH3:29]>>[NH2:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][CH:10]=[C:9]([C:24]3[C:25]([CH3:31])=[N:26][N:27]([CH3:30])[C:28]=3[CH3:29])[CH:8]=2)[C:5]2[CH:19]=[CH:20][CH:21]=[CH:22][C:4]=2[N:3]=1

Participants

3

Reactant 2

HCID 5191814-Bromo-1,3,5-trimethylpyrazoleHCID 18522055HCID 18522055, compound

Product 1

HCID 185220732-Amino-1-[3-(1,3,5-trimethyl-4-pyrazolyl)phenyl]benzimidazole

Procedure

2-Amino-1-[3-(1,3,5-trimethyl-4-pyrazolyl)phenyl]benzimidazole was prepared from 3-(2-amino-1-benzimidazolyl)-phenyl-1,3,2-dioxaborinane and 4-bromo- 1,3,5-trimethylpyrazole by method A. mp 198°-200° C.

Sources & evidence

ORD record
ord-9f907be934c94e76822aba7ce40366fb
Source dataset
uspto-grants-1995_08
Patent number
US05441969

Reaction notes

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