HCID 19390950, compound → 2-Amino-1-[3-(3-methoxymetyl-2-furyl)-4-methylphenyl]benzimidazole

HRID 1756647Notes

Reaction equation

HRID 1756647 reaction equation
[NH2:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][C:10]([CH3:13])=[C:9](I)[CH:8]=2)[C:5]2[CH:15]=[CH:16][CH:17]=[CH:18][C:4]=2[N:3]=1.[CH3:19][O:20][CH2:21][C:22]1[CH:26]=[CH:25][O:24][C:23]=1[Sn](C)(C)C>>[NH2:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][C:10]([CH3:13])=[C:9]([C:23]3[O:24][CH:25]=[CH:26][C:22]=3[CH2:21][O:20][CH3:19])[CH:8]=2)[C:5]2[CH:15]=[CH:16][CH:17]=[CH:18][C:4]=2[N:3]=1

Participants

3

Reactant 2

HCID 19390950HCID 19390950, compoundHCID 193909784-(2-Amino-1-benzimidazolyl)-2-iodotoluene

Product 1

HCID 193909572-Amino-1-[3-(3-methoxymetyl-2-furyl)-4-methylphenyl]benzimidazole

Procedure

2-Amino-1-[3-(3-methoxymetyl-2-furyl)-4-methylphenyl]benzimidazole was prepared from 4-(2-amino-1-benzimidazolyl)-2-iodotoluene and 3-methoxymethyl-2-trimethylstannylfuran according to method C. mp 174°-176° C.

Sources & evidence

ORD record
ord-76e4d13a96e24f18b626189b1010261e
Source dataset
uspto-grants-1995_08
Patent number
US05441969

Reaction notes

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