2-(Trimethylstannyl)furan → 2-Amino-1-[3-(2-furyl)-4-methylphenyl]benzimidazole

HRID 1756648Notes

Reaction equation

HRID 1756648 reaction equation
[NH2:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][C:10]([CH3:13])=[C:9](I)[CH:8]=2)[C:5]2[CH:15]=[CH:16][CH:17]=[CH:18][C:4]=2[N:3]=1.C[Sn](C)(C)[C:21]1[O:22][CH:23]=[CH:24][CH:25]=1>>[NH2:1][C:2]1[N:6]([C:7]2[CH:12]=[CH:11][C:10]([CH3:13])=[C:9]([C:21]3[O:22][CH:23]=[CH:24][CH:25]=3)[CH:8]=2)[C:5]2[CH:15]=[CH:16][CH:17]=[CH:18][C:4]=2[N:3]=1

Participants

3

Reactant 2

HCID 98133762-(Trimethylstannyl)furanHCID 193909784-(2-Amino-1-benzimidazolyl)-2-iodotoluene

Product 1

HCID 193909642-Amino-1-[3-(2-furyl)-4-methylphenyl]benzimidazole

Procedure

2-Amino-1-[3-(2-furyl)-4-methylphenyl]benzimidazole was prepared from 4-(2-amino-1-benzimidazolyl)-2-iodotoluene and 2-trimethylstannylfuran according to method C. mp 155°-157° C.

Sources & evidence

ORD record
ord-e1151d07b0ba4204aab2070d1e274ea3
Source dataset
uspto-grants-1995_08
Patent number
US05441969

Reaction notes

Loading…