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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1756661Generated: October 28, 2026

4-Benzylpiperidine → 1-Acetyl-4-[2,4-di[(4-benzyl)piperidino]benzoyl]piperidine

https://huagongshe.com/reaction/1756661

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-BenzylpiperidineHCID 31738—
Reactant1-Acetyl-4-(2',4'-difluorobenzoyl)piperidineHCID 2740707—
Product1-Acetyl-4-[2,4-di[(4-benzyl)piperidino]benzoyl]piperidineHCID 15290035—

Reaction Conditions

Temperature100 °C

Reaction Steps

A mixture consisting of 2.67 g of 1-acetyl-4-(2,4-difluorobenzoyl)piperidine and 8.8 ml of 4-benzylpiperidine was stirred at 100° C. for 24 hours and the reaction mixture was then worked up in the same manner as Example 2 to give 4.1 g of the title compound as oil.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS05441967
Source datasetuspto-grants-1995_08
ORD IDord-af9eb24946eb466685ddcea7836dad4a
Source noteuspto-grants-1995_08