HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Methylthio)aniline → N-[4-(Methylsulfanyl)phenyl]urea
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Methylthio)aniline | HCID 66038 | — |
| Reactant | Sodium Cyanate | HCID 517096 | — |
| Solvent | Acetic Acid | HCID 176 | — |
| Solvent | Water | HCID 962 | — |
| Product | N-[4-(Methylsulfanyl)phenyl]urea | HCID 306638 | 96.8% |
Reaction Steps
A solution of 30 g (170 mmol) of 4-(methylmercapto)aniline dissolved in 83 ml of acetic acid and 165 ml of water was heated to 40° C. Once warmed to 40° C. a solution of sodium cyanate (22.2 g; 340 mmol) in 150 ml of water was slowly added. The resulting suspension was stirred for 15 minutes and then allowed to sit for 2 hours. Filtration of the suspension provided 29.98 g of title compound. m.p. 155°-159° C.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05441984 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-5a859bdb13594bed8f802d6f1328b913 |
| Source note | uspto-grants-1995_08 |