Thionyl Chloride → HCID 54108381, compound

HRID 1756771Notes

Reaction equation

HRID 1756771 reaction equation
[CH:1]([C:4]1[CH:11]=[CH:10][CH:9]=[C:8]([CH:12]([CH3:14])[CH3:13])[C:5]=1[CH2:6]O)([CH3:3])[CH3:2].S(Cl)([Cl:17])=O>C1(C)C=CC=CC=1>[CH:1]([C:4]1[CH:11]=[CH:10][CH:9]=[C:8]([CH:12]([CH3:14])[CH3:13])[C:5]=1[CH2:6][Cl:17])([CH3:3])[CH3:2]

Participants

4

Reactant 2

HCID 24386Thionyl ChlorideHCID 45117178[2,6-Di(propan-2-yl)phenyl]methanol

Product 1

HCID 54108381HCID 54108381, compoundYield 99.3%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent

Procedure

To a solution of 1.37 g (7.12 mmol) of 2, 6-diisopropylbenzyl alcohol in 20 ml of toluene was added 0.78 ml (10.7 mmol) of thionyl chloride, and the resultant mixture was stirred at room temperature for 3.5 hours. The reaction mixture was washed with water, dried over anhydrous magnesium sulfate and the solvent evaporated in vacuo to give 1.49 g of 2, 6-diisopropylbenzyl chloride as an oil.

Workup

  1. washThe reaction mixture was washed with water
  2. dry with materialdried over anhydrous magnesium sulfate
  3. customthe solvent evaporated in vacuo

Sources & evidence

ORD record
ord-23c7f3a620a7481f9b504a21409aa50a
Source dataset
uspto-grants-1995_08
Patent number
US05442060

Reaction notes

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