HCID 178501207, compound → HCID 19391441, compound
Reaction equation
[C:1]([C:3]1[CH:8]=[CH:7][C:6]([N:9]2[CH2:14][CH2:13][CH:12]([C:15]([NH:17][C@H:18]3CC[C@H:21]([C:24]([O:26][CH3:27])=[O:25])[CH2:20][CH2:19]3)=[O:16])[CH2:11][CH2:10]2)=[CH:5][CH:4]=1)#[N:2].N[C@H:29]1CC[C@H](C(OC)=O)C[CH2:30]1>>[C:1]([C:3]1[CH:4]=[CH:5][C:6]([N:9]2[CH2:10][CH2:11][CH:12]([C:15]([N:17]3[CH2:30][CH2:29][CH:20]([CH2:21][C:24]([O:26][CH3:27])=[O:25])[CH2:19][CH2:18]3)=[O:16])[CH2:13][CH2:14]2)=[CH:7][CH:8]=1)#[N:2]Participants
3
Procedure
1-(4-cyanophenyl)-4-[N-[trans-4-(methoxycarbonyl)-cyclohexyl]-aminocarbonyl]-piperidine Using methyl trans-4-amino-cyclohexanecarboxylate. Melting point: 230°-232° C.
Sources & evidence
- ORD record
- ord-da8f35b426134ccf905696cf1d3f2534
- Source dataset
- uspto-grants-1995_08
- Patent number
- US05442064
Reaction notes
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