HCID 10626637, compound → HCID 10548421, compound

Participants

Reaction Steps

In a dry 50 ml flask under nitrogen, methyl 3-(2-(2,3,4,6-tetra-O-acetyl-α-D-mannopyranosyloxy)phenyl)benzoate (2.18 g, 3.9 mmol) was dissolved in methanol (20 ml) and treated in one portion with sodium methoxide (250 mg) and the mixture was stirred at room temperature overnight, then concentrated under reduced pressure. The residue was purified by flash chromatography (SiO2, 7:3 methylene chloride/methanol) which gave methyl 3-(2-(α-D-mannopyranosyloxy)phenyl)benzoate in 84% yield.

Provenance & Evidence