Ethyl benzoylacetate → ethyl 2-bromo-3-oxo-3-phenylpropanoate

Participants

Reaction Conditions

Reaction Steps

25 ml (0.144 mol) of ethyl benzoyl acetate are dissolved in 50 ml of CCl4, 8.5 ml of bromine are added dropwise at 5° C. and the brown solution is stirred at 5° C. for 1 h, at room temperature for 3 h and at 60° C. for 2 h. It is concentrated to dryness, the residue is taken up in EA, the EA solution is washed with 10% strength Na2SO3 solution and satd. NaCl solution, dried over MgSO4 and concentrated, and the residue is dried in a high vacuum. 38 g of the title compound result as a red oil.

Provenance & Evidence