Methanesulfonyl chloride → 3-{[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-methanesulfonyl-amino}-piperidine-1-carboxylic acid tert-butyl ester

HRID 175714Notes

Reaction equation

HRID 175714 reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([NH:14][CH2:15][c:16]2[cH:17][c:18](-[c:22]3[n:23][c:24]([Cl:28])[n:25][cH:26][cH:27]3)[cH:19][cH:20][cH:21]2)[CH2:11][CH2:12][CH2:13]1.[CH3:29][S:30]([Cl:31])(=[O:32])=[O:33]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([N:14]([CH2:15][c:16]2[cH:17][c:18](-[c:22]3[n:23][c:24]([Cl:28])[n:25][cH:26][cH:27]3)[cH:19][cH:20][cH:21]2)[S:30]([CH3:29])(=[O:32])=[O:33])[CH2:11][CH2:12][CH2:13]1

Participants

3

Reactant 2

HCID 31297Methanesulfonyl chlorideHCID 866032653-[3-(2-Chloro-pyrimidin-4-yl)-benzylamino]-piperidine-1-carboxylic acid tert-butyl ester

Product 1

HCID 866032753-{[3-(2-Chloro-pyrimidin-4-yl)-benzyl]-methanesulfonyl-amino}-piperidine-1-carboxylic acid tert-butyl ester

Sources & evidence

ORD record
ord-b1122f0509ff4df882f49e6a842575ad
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (6/10)

Reaction notes

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