HuagongsheHuagongshe Chemistry Print Report · For research reference only
Dimethylformamide → (E,E,E)-2-(6,6-dimethyl-2-hepten-4-ynyl)-8-[3-[3-thienyl)phenyl]-2,7-octadienic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Dimethylformamide | HCID 6228 | — |
| Reactant | Sodium hydride | HCID 24758 | — |
| Reactant | 5-Bromopentanenitrile | HCID 79435 | — |
| Reactant | 3-(Thiophen-3-YL)phenol | HCID 4130343 | — |
| Reactant | 5-[3-(3-Thienyl)phenoxy]valeronitrile | HCID 19390154 | — |
| Reactant | HCID 19390157 | HCID 19390157 | — |
| Product | (E,E,E)-2-(6,6-dimethyl-2-hepten-4-ynyl)-8-[3-[3-thienyl)phenyl]-2,7-octadienic acid methyl ester | HCID 15288593 | — |
Reaction Steps
(E,E)-2-(6,6-dimethyl-2-hepten-4-ynyl)-7-[3-(3-thienyl)phenoxy]-2-heptenoic acid methyl ester is obtained by carrying out the same reactions as in Referential Example 1 except that 5-[3-(3-thienyl)phenoxy]valeronitrile [synthesized by condensing 3-(3-thienyl)phenol with 5-bromovaleronitrile in dimethylformamide in the presence of sodium hydride] is used in place of (E)-6-[3-(3-thienyl)phenyl]-5-hexenenitrile which is the raw material compound used in the above.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05444084 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-41556c49247e4e76bfb432fc041fb349 |
| Source note | uspto-grants-1995_08 |