Dichloromethane → HCID 54097921, compound

Participants

Reaction Steps

A methylene chloride solution (2 ml) of 126 mg of 2-[2-[3-(3-thienyl)phenoxy]ethoxy]ethanol is added to a mixed solution of 352 mg of pyridinium chlorochromate, 274 mg of sodium acetate, 130 mg of molecular sieves (4A) and 5 ml of methylene chloride, the mixture is stirred at room temperature for 1.5 hours, the reaction solution is diluted with ethyl ether, silica gel is added, and the insoluble matters are removed by filtration. The filtrate is concentrated under reduced pressure, and the residue is purified by silica gel column chromatography [Wako gel C-200, 10 g; hexane/ethyl acetate=4/1→2/1] to obtain 45 mg of the captioned compound as colorless oil.

Provenance & Evidence