Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Carbon Dioxide → Boc-Leu-DTrp-NHNH2
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Carbon Dioxide | HCID 280 | — |
| 반응물 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 반응물 | Boc-Leu-DTrp-OMe | HCID 14504288 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 생성물 | Boc-Leu-DTrp-NHNH2 | HCID 11070055 | — |
반응 단계
To a solution of the compound obtained in (1) (430 mg) in DMF (10 ml) was added hydrazine monohydrate (1.0 ml) at room temperature and the solution was stirred overnight. To the reaction mixture was added dry-ice and the resulting solution was concentrated to give a residue, which was triturated with water to afford the product (406 mg).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05444152 |
| 출처 데이터셋 | uspto-grants-1995_08 |
| ORD ID | ord-11c5c2fc20bc42f8987769e7d44295fe |
| 출처 메모 | uspto-grants-1995_08 |