Pivaloyl chloride → 4, 13-Bis(tert.-butylcarbonyl)-1,7,10,16-tetraoxa-4,13-diazacyclooctadecane

HRID 1757313Notes

Reaction equation

[O:1]1[CH2:18][CH2:17][O:16][CH2:15][CH2:14][NH:13][CH2:12][CH2:11][O:10][CH2:9][CH2:8][O:7][CH2:6][CH2:5][NH:4][CH2:3][CH2:2]1.[C:19](Cl)(=[O:24])[C:20]([CH3:23])([CH3:22])[CH3:21]>>[C:20]([C:19]([N:4]1[CH2:5][CH2:6][O:7][CH2:8][CH2:9][O:10][CH2:11][CH2:12][N:13]([C:19]([C:20]([CH3:23])([CH3:22])[CH3:21])=[O:24])[CH2:14][CH2:15][O:16][CH2:17][CH2:18][O:1][CH2:2][CH2:3]1)=[O:24])([CH3:23])([CH3:22])[CH3:21]

Participants

Reactant 2

HCID 62493Pivaloyl chloride

HCID 72805Diaza-18-crown-6

Product 1

HCID 218041604, 13-Bis(tert.-butylcarbonyl)-1,7,10,16-tetraoxa-4,13-diazacyclooctadecane

Procedure

Analogously to Example 2 from 1,7,10,16-tetraoxa-4,13-diazacyclooctadecane and pivalyl chloride.

Sources & evidence

ORD record: ord-0406ab6006d042acbd279fd7e0ecd6f3
Source dataset: uspto-grants-1995_08
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US05445762

Reaction notes

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