HCID 178444298, compound → HCID 178443737, compound

HRID 1757369Notes

Reaction equation

HRID 1757369 reaction equation
[F:1][C:2]1[C:3]([C:9]2[CH:14]=[CH:13][C:12]([C@H:15]3[CH2:20][CH2:19][C@H:18]([CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[CH2:17][CH2:16]3)=[CH:11][CH:10]=2)=[N:4][CH:5]=[C:6]([OH:8])[CH:7]=1>C(O)CCCCCCC>[F:1][C:2]1[C:3]([C:9]2[CH:14]=[CH:13][C:12]([C@H:15]3[CH2:20][CH2:19][C@H:18]([CH2:21][CH2:22][CH2:23][CH2:24][CH3:25])[CH2:17][CH2:16]3)=[CH:11][CH:10]=2)=[N:4][CH:5]=[C:6]([O:8][CH2:6][CH2:7][CH2:2][CH2:3][CH2:9][CH2:10][CH2:11][CH3:12])[CH:7]=1

Participants

3

Reactant 1

HCID 178444298HCID 178444298, compound

Product 1

HCID 178443737HCID 178443737, compound

Reagents, catalysts & solvents 1

HCID 9571-OctanolSolvent

Procedure

Octanol and 3-fluoro-5-hydroxy-2-[4-(trans-4-pentylcyclohexyl)phenyl]pyridine are reacted analogously to Example 2 to give 3-fluoro-5-octyloxy-2-[4-(trans-4pentylcyclohexyl)phenyl]pyridine. ##STR38##

Sources & evidence

ORD record
ord-faf307ed03ea4c598ad5545bd056054a
Source dataset
uspto-grants-1995_08
Patent number
US05445763

Reaction notes

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