HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Hydroxyquinoline → HCID 19387693, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Hydroxyquinoline | HCID 6038 | — |
| Reactant | Triethylamine | HCID 8471 | — |
| Reactant | Benzothiazolium, 3-methyl-2-(methylthio)-, 4-methylbenzenesulfonate (1:1) | HCID 41464 | — |
| Reactant | N-Cyclohexylaniline | HCID 74567 | — |
| Reactant | HCID 19387694 | HCID 19387694 | — |
| Product | HCID 19387693 | HCID 19387693 | — |
Reaction Steps
1-Cyclohexyl-1,2-dihydro-4-methyl-2-quinolone is prepared using N-cyclohexylaniline as starting material. The quinolone (0.482 g, 2 mmol) is transformed to the 2-chloro-1-cyclohexylquinolinium chloride with a procedure similar to Example 3, and is then reacted with 3-methyl-2-methylthiobenzothiazolium tosylate (0.74 g, 2 mmol) and triethylamine (0.28 mL, 2 mmol) to yield the product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US05445946 |
| Source dataset | uspto-grants-1995_08 |
| ORD ID | ord-b267233e487c48408ca248b9f00031fd |
| Source note | uspto-grants-1995_08 |