beta-Maltose → HCID 86748941, compound

Participants

Reaction Steps

A 1-liter eggplant type flask equipped with a reflux condenser was charged with 22.7 g (72 mmol) of 1-amino-3-hexadecyloxy-2-propanol, 23.5 g (69 mmol) of maltose and 350 g of methanol. After stirring the mixture for 20 hours at room temperature under a nitrogen atmosphere, it was heated and stirred at 80° C. for 1 hour. The thus-obtained solution was transferred to a 970-ml autoclave, and 2.26 g of palladium on carbon was added, thereby subjecting the solution to hydrogenolysis at 50° C. for 16 hours under a hydrogen pressure of 100 kg/cm2. The catalyst was removed by filtering the hot mixture, and the filtrate was allowed to cool to form crystals. The crystals were recrystallized again from methanol, thereby obtaining 15.2 g (yield: 33%) of the title compound (2Be) as a colorless solid.

Provenance & Evidence